User profiles for M. Stephens

Matthew Stephens

University of Chicago
Verified email at uchicago.edu
Cited by 132256

[HTML][HTML] Stress and the HPA axis: role of glucocorticoids in alcohol dependence

MAC Stephens, G Wand - Alcohol research: current reviews, 2012 - ncbi.nlm.nih.gov
Stress has long been suggested to be an important correlate of uncontrolled drinking and
relapse. An important hormonal response system to stress—the hypothalamic–pituitary–…

The pathogenesis of hallux valgus

AM Perera, L Mason, MM Stephens - JBJS, 2011 - journals.lww.com
The first ray is an inherently unstable axial array that relies on a fine balance between its
static (capsule, ligaments, and plantar fascia) and dynamic stabilizers (peroneus longus and …

Bayesian statistical methods for genetic association studies

M Stephens, DJ Balding - Nature Reviews Genetics, 2009 - nature.com
… & Stephens, M. Imputation-based analysis of association studies: candidate regions and …
& Stephens, M. Practical issues in imputation-based association mapping. PLoS Genet. …

The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans

…, DL Nicolae, NJ Cox, T Flutre, X Wen, M Stephens… - Science, 2015 - science.org
Understanding the functional consequences of genetic variation, and how it affects complex
human disease and quantitative traits, remains a critical challenge for biomedicine. We …

Inferring weak population structure with the assistance of sample group information

MJ Hubisz, D Falush, M Stephens… - Molecular ecology …, 2009 - Wiley Online Library
Genetic clustering algorithms require a certain amount of data to produce informative results.
In the common situation that individuals are sampled at several locations, we show how …

[PDF][PDF] A combined corner and edge detector

C Harris, M Stephens - Alvey vision conference, 1988 - Citeseer
… Let a,P be the eigenvalues of M. a and P will be proportional to the principal curvatures of …
Tr(M) and Det(M) in the formulation, as this avoids the explicit eigenvalue decomposition of M, …

[PDF][PDF] The treatment-naive microbiome in new-onset Crohn's disease

…, T Walters, S Baker, J Rosh, M Stephens, M Heyman… - Cell host & …, 2014 - cell.com
Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), are genetically linked
to host pathways that implicate an underlying role for aberrant immune responses to …

RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays

JC Marioni, CE Mason, SM Mane, M Stephens… - Genome …, 2008 - genome.cshlp.org
Ultra-high-throughput sequencing is emerging as an attractive alternative to microarrays for
genotyping, analysis of methylation patterns, and identification of transcription factor binding …

[PDF][PDF] A comparison of bayesian methods for haplotype reconstruction from population genotype data

M Stephens, P Donnelly - The American Journal of Human Genetics, 2003 - cell.com
In this report, we compare and contrast three previously published Bayesian methods for
inferring haplotypes from genotype data in a population sample. We review the methods, …

[PDF][PDF] A new statistical method for haplotype reconstruction from population data

M Stephens, NJ Smith, P Donnelly - The American Journal of Human …, 2001 - cell.com
… for all h, where M is the total number of different possible haplotypes that could be observed
in the population, 1/M then we can solve these problems by exploiting the fact that, for those …