In recent years, there have been multiple advances in positron emission tomography/computed
tomography (PET/CT) that improve cancer imaging. The present generation of PET/CT …

Cardiac imaging has a pivotal role in the prevention, diagnosis and treatment of ischaemic
heart disease. SPECT is most commonly used for clinical myocardial perfusion imaging, …

Amide bonds occur in over half of target compounds in medicinal chemistry patents, making
amide bond formation the most commonly performed reaction in the pharmaceutical industry…

Current strategies combining anti-angiogenic drugs with chemotherapy provide clinical
benefit in cancer patients. It is assumed that anti-angiogenic drugs, such as bevacizumab, …

A major pathological hallmark of Alzheimer's disease is accumulation of amyloid-β in senile
plaques in the brain. Evidence is accumulating that decreased clearance of amyloid-β from …

Objectives : This study was designed to evaluate myocardial substrate and high-energy
phosphate (HEP) metabolism in asymptomatic men with well-controlled, uncomplicated type 2 …

The organs at risk in radionuclide therapy with 177 Lu-octreotate are the bone marrow and
the kidneys. The primary aim of this study was to develop an individualized dosimetry …

Background— Cardiac disease is the leading cause of mortality in type 2 diabetes mellitus (T2DM).
Pioglitazone has been associated with improved cardiac outcome but also with an …

The expression status of human epidermal growth factor receptor type 2 (HER2) predicts
the response of HER2-targeted therapy in breast cancer. ABY-025 is a small reengineered …

Purpose: Positron Emission Tomography (PET) imaging of HER2 expression could potentially
be used to select patients for HER2-targed therapy, predict response based on uptake …