Unveiling Cytokine Charge Disparity as a Potential Mechanism for Immune Regulation

JM Messina, M Luo, MS Hossan, HA Gadelrab… - Cytokine & Growth …, 2023 - Elsevier
Cytokines are small signaling proteins that regulate the immune responses to infection and
tissue damage. Surface charges of cytokines determine their in vivo fate in immune regulation…

Telodendrimer functionalized hydrogel platform for sustained antibiotics release in infection control

X Yang, D Guo, X Ji, C Shi, JM Messina, L Suo, J Luo - Acta Biomaterialia, 2024 - Elsevier
Wound infection commonly causes delayed healing, especially in the setting of chronic wounds.
Local release of antibiotics is considered a viable approach to treat chronic wounds. We …

First investigation of RH gene polymorphism in patients with sickle cell disease and associated blood donors in Cameroon, Central Africa

…, J Tchatchueng, AN Nloga, Y Fichou, JM Messina - Blood …, 2024 - hal.science
Although genetic polymorphism of the RH blood group system is well known in sub-Saharan
Africa, national/regional specificities still remain to be described precisely. For the first time …

Functionalized Core–Shell Nanogel Scavenger for Immune Modulation Therapy in Sepsis

…, C Shi, D Guo, X Wang, JM Messina… - Advanced …, 2022 - Wiley Online Library
Sepsis is a complex, life‐threatening hyperinflammatory syndrome associated with organ
failure and high mortality due to lack of effective treatment options. Here, a core–shell hydrogel …

Friendly strategy to prepare encoded one bead–one compound cyclic peptide library

SL Giudicessi, JM Gurevich-Messina… - ACS Combinatorial …, 2013 - ACS Publications
One bead–one peptide libraries allow the screening of suitable ligands for any target protein.
Short cyclic peptides are ideal ligands for affinity chromatography because of their high …

A simple protocol for combinatorial cyclic depsipeptide libraries sequencing by matrix‐assisted laser desorption/ionisation mass spectrometry

JM Gurevich‐Messina, SL Giudicessi… - Journal of Peptide …, 2015 - Wiley Online Library
Short cyclic peptides have a great interest in therapeutic, diagnostic and affinity
chromatography applications. The screening of ‘one‐bead‐one‐peptide’ combinatorial libraries …

Combinatorial library screening coupled to mass spectrometry to identify valuable cyclic peptides

…, JM Gurevich‐Messina… - Current Protocols in …, 2016 - Wiley Online Library
Combinatorial library screening coupled to mass spectrometry (MS) analysis is a practical
approach to identify useful peptides. Cyclic peptides can have high biological activity, …

Recombinant human follicle stimulating hormone purification by a short peptide affinity chromatography

JM Gurevich Messina, SL Giudicessi… - Journal of Peptide …, 2018 - Wiley Online Library
Peptide KVPLITVSKAK was selected to design a synthetic ligand for affinity chromatography
purification of recombinant human follicle stimulating hormone (rhFSH), based on the …

Mass spectrometry-based metabolic fingerprinting contributes to unveil the role of RSUME in renal cell carcinoma cell metabolism

…, L Tedesco, JM Gurevich Messina… - Journal of Proteome …, 2020 - ACS Publications
Clear cell renal cell carcinoma (ccRCC) is a heterogeneous disease with 50–80% patients
exhibiting mutations in the von Hippel–Lindau (VHL) gene. RSUME (RWD domain (termed …

Manipulation of Mg2+–Ca2+ Switch on the Development of Bone Mimetic Hydroxyapatite

…, VL Massheimer, PV Messina - … applied materials & …, 2017 - ACS Publications
Ionic substitution can affect essential physicochemical properties leading to a specific biological
behavior upon implantation. Therefore, it has been proposed as a tool to increase the …