User profiles for J. D. Stewart

Joanna Dawn Stewart

Associate Lecturer, Open University
Verified email at open.ac.uk
Cited by 2661

Foot drop: where, why and what to do?

JD Stewart - Practical neurology, 2008 - pn.bmj.com
… (Reproduced with permission from Stewart JD. Focal peripheral neuropathies. Third edition.
… (Reproduced with permission from Stewart JD. Focal peripheral neuropathies. Third edition. …

Peripheral nerve fascicles: anatomy and clinical relevance

JD Stewart - Muscle & nerve, 2003 - Wiley Online Library
Within a peripheral nerve, the individual nerve fibers are grouped together in fascicles.
Whether there is somatotopic organization within these fascicles has long been of interest, the …

Dehydrogenases and transaminases in asymmetric synthesis

JD Stewart - Current Opinion in Chemical Biology, 2001 - Elsevier
… Rodriguez S, Kayser MM, Stewart JD: Highly stereoselective reagents for β-keto ester
reductions by genetic engineering of baker's yeast. J Am Chem Soc 2001, in press. The potential …

[HTML][HTML] An epigenetic biomarker of aging for lifespan and healthspan

…, S Bandinelli, L Hou, AA Baccarelli, JD Stewart… - Aging (albany …, 2018 - ncbi.nlm.nih.gov
Identifying reliable biomarkers of aging is a major goal in geroscience. While the first
generation of epigenetic biomarkers of aging were developed using chronological age as a …

[HTML][HTML] DNA methylation GrimAge strongly predicts lifespan and healthspan

…, K Raj, L Hou, AA Baccarelli, Y Li, JD Stewart… - Aging (albany …, 2019 - ncbi.nlm.nih.gov
It was unknown whether plasma protein levels can be estimated based on DNA methylation
(DNAm) levels, and if so, how the resulting surrogates can be consolidated into a powerful …

[HTML][HTML] Autoantibodies to ganglionic acetylcholine receptors in autoimmune autonomic neuropathies

…, PA Low, RD Fealey, JD Stewart… - … England Journal of …, 2000 - Mass Medical Soc
Background Idiopathic autonomic neuropathy is a severe, subacute disorder with a presumed
autoimmune basis. It is indistinguishable from the subacute autonomic neuropathy that …

[HTML][HTML] Epigenetic clock analysis of diet, exercise, education, and lifestyle factors

…, PS Tsao, D Absher, TL Assimes, JD Stewart… - Aging (albany …, 2017 - ncbi.nlm.nih.gov
Behavioral and lifestyle factors have been shown to relate to a number of health-related
outcomes, yet there is a need for studies that examine their relationship to molecular aging rates…

Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: a novel disorder of …

G Hudson, P Amati-Bonneau, EL Blakely, JD Stewart… - Brain, 2008 - academic.oup.com
Mutations in nuclear genes involved in mitochondrial DNA (mtDNA) maintenance cause a
wide range of clinical phenotypes associated with the secondary accumulation of multiple …

Multi-system neurological disease is common in patients with OPA1 mutations

…, MP Clarke, B Dhillon, B Czermin, JD Stewart… - Brain, 2010 - academic.oup.com
Additional neurological features have recently been described in seven families transmitting
pathogenic mutations in OPA1, the most common cause of autosomal dominant optic …

[HTML][HTML] Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies

…, A Aviv, L Hou, AA Baccarelli, Y Li, JD Stewart… - Aging (Albany …, 2018 - ncbi.nlm.nih.gov
DNA methylation (DNAm)-based biomarkers of aging have been developed for many tissues
and organs. However, these biomarkers have sub-optimal accuracy in fibroblasts and other …