User profiles for M. Ruff

Michael W Ruff

Assistant Professor, Mayo Clinic
Verified email at mayo.edu
Cited by 732

HSPA8/HSC70 chaperone protein: structure, function, and chemical targeting

F Stricher, C Macri, M Ruff, S Muller - Autophagy, 2013 - Taylor & Francis
HSPA8/HSC70 protein is a fascinating chaperone protein. It represents a constitutively
expressed, cognate protein of the HSP70 family, which is central in many cellular processes. In …

Important parasites in poultry production systems

MD Ruff - Veterinary parasitology, 1999 - Elsevier
Poultry now accounts for 30% of all meat consumed. Parasites are a problem where ever
poultry are raised, whether in large commercial operations or in small back-yard flocks, and …

[HTML][HTML] Estrogen receptor transcription and transactivation Structure-function relationship in DNA-and ligand-binding domains of estrogen receptors

M Ruff, M Gangloff, J Marie Wurtz, D Moras - Breast Cancer Research, 2000 - Springer
Estrogen receptors are members of the nuclear receptor steroid family that exhibit specific
structural features, ligand-binding domain sequence identity and dimeric interactions, that …

[HTML][HTML] Identifying small molecules via high resolution mass spectrometry: communicating confidence

EL Schymanski, J Jeon, R Gulde, K Fenner, M Ruff… - 2014 - ACS Publications
The increased availability of high resolution mass spectrom-etry (HR-MS) in chemical
analysis has dramatically improved the detection and identification of compounds in …

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α

W Bourguet, M Ruff, P Chambon, H Gronemeyer… - Nature, 1995 - nature.com
… For soaking with PCMBS, all crystals were first stabilised in 2 M ammonium citrate (pH 7.0)
and then transferred into 1.8 M ammonium sulphate at the same pH. Data collection, phase …

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

JP Renaud, N Rochel, M Ruff, V Vivat, P Chambon… - Nature, 1995 - nature.com
The 2.0-Å crystal structure of the ligand-binding domain (LBD) of the human retinoic acid
receptor (RAR)-γ bound to all-trans retinoic acid reveals the ligand-binding interactions and …

Class II Aminoacyl Transfer Rna Synthetases: Crystal Structure of Yeast Aspartyl-trna Synthetase Complexed with tRNAAsp

M Ruff, S Krishnaswamy, M Boeglin, A Poterszman… - Science, 1991 - science.org
The crystal structure of the binary complex tRNA Asp -aspartyl tRNA synthetase from yeast
was solved with the use of multiple isomorphous replacement to 3 angstrom resolution. The …

[PDF][PDF] Neuropeptides and their receptors: a psychosomatic network

CB Pert, MR Ruff, RJ Weber, M Herkenham - 1985 - Citeseer
… (-)-naloxone but unaffected by the same (1 0-8 M) concentration of its pharmacologically …
Cells were washed twice in 0.05 M Tris. 0.15 M NaCI. pH 7.4, and were suspended in a total …

Phylogenetic relationships among eight Eimeria species infecting domestic fowl inferred using complete small subunit ribosomal DNA sequences

…, MC Jenkins, HD Danforth, MD Ruff… - The Journal of …, 1997 - JSTOR
… Purified geno added to a reaction mixture containing 10 m 50 mM KCI, 1.5 mM MgCI2,
0.001% gelatin U Taq DNA polymerase, and 1 I[M of each of primers (ERIB 1 and ERIB 10). The …

SiC devices: physics and numerical simulation

M Ruff, H Mitlehner, R Helbig - IEEE Transactions on electron …, 1994 - ieeexplore.ieee.org
The important material parameters for 6H silicon carbide (6H-SiC) are extracted from the
literature and implemented into the 2-D device simulation programs PISCES and …