Pertussis, or whooping cough, is a highly contagious, acute respiratory disease of humans
that is caused by the Gram-negative bacterial pathogen Bordetella pertussis. In the face of …

… (D) The production of type I IFNs by epithelial cells and innate immune cells also inhibits
the recruitment of PMNs and macrophages from the periphery through the IL-23–IL-17 axis. (E) …

Differences in susceptibility to immune-mediated diseases are determined by variability in
immune responses. In three studies within the Human Functional Genomics Project, we …

Before childhood vaccination was introduced in the 1940s, pertussis was a major cause of
infant death worldwide. Widespread vaccination of children succeeded in reducing illness …

The resurgence and changing epidemiology of pertussis in high-income countries, the high
infant mortality caused by pertussis in low-income countries, and the increasing morbidity in …

Bordetella pertussis, B. bronchiseptica, B. parapertussis hu , and B. parapertussis ov are
closely related respiratory pathogens that infect mammalian species. B. pertussis and B. …

The tuberculosis vaccine bacillus Calmette-Guérin (BCG) protects against some heterologous
infections, probably via induction of non-specific innate immune memory in monocytes …

… 2 d following pneumococcal colonization (d 1). In antibody treatment was repeated daily at d
0… A) Three days following pneumococcal colonization (d 0), index mice were infected in with …

Background. Influenza-related morbidity and mortality remain high. Seasonal vaccination is
the backbone of influenza management but does not always result in protective antibody …

Although serological studies have shown that antibodies against SARS-CoV-2 play an
important role in protection against (re)infection, the dynamics of mucosal antibodies during …